HUMAN HEALTH & NUTRITION — Plant/Herb Extracts
Ginkgo Biloba Extract

Manufacturer is GMP certificated with supportive certificates of HACCP,KOSHER and HALAL.
 
1.Description

Ginkgo biloba tree,ofen referred as a living fossil with wild species only found in central China, is today widely planted for cultivation and ornamental purpose across the urban area. Ginkgo biloba extract has proven effective in treatment of circulatory and neurological conditions.

Our supply of Ginkgo biloba extract (GBE) is a kind of yellow brown powder. The main active constituents include terpene lactones and flavone glycosides. Cas No.: 90045-36-6

 

2.Chemical Structure

R=OH Quercertin(bilobalide) derivative
R=H Kaempferol derivative
R=OCH3 Isorhamnetin derivative

R1=OH, R2=R3=H Ginkgolide A
R1=R2=OH, R3=H Ginkgolide B
R1=R2=R3=OH Ginkgolide C

 

3.Quality Specification

Items Chinese Pharmacopoeia 2015 Factory in-house Standard
Appearance Yellow-brown powder, a slight bitter taste
Loss on drying ≤5.0% ≤4.0%
Residue on ignition ≤0.8% ≤0.8%
Peak area ratio of flavoniod glycones Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15. Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15. Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15. Peak area ratio of quercetin and kaempferol should be in the range of 0.8-1.2; peak area ratio of isorhamnetion and quercetin should be not less than 0.15.
Total Ginkgolic acid ≤10mg/kg ≤5mg/kg
Total Flavone glycosides ≥24.0% ≥24.30%
Total Terpene lactones ≥6.0% ≥6.35%
Free quercetin / ≤10.0mg/g
Free kaempferol / ≤10.0mg/g
Free isorhamnetion / ≤4.0mg/g
Total plate count(cfu/g) ≤1000 ≤800
Mould & Yeast(cfu/g) ≤100 ≤50
E.coil(1g) Not detected Not detected
 

Regular presentation:
Water soluble grade:
Flavone glycosides 24% / Terpene lactones 6%

 

CP2015 grade:
Flavone glycosides 24% / Terpene lactones 6% ginkgolic acid <5ppm

 

USP 38 Grade:
Flavone glycosides 22~27% / Terpene lactones 5.4~12.00% / Ginkgolic Acid<5PPM / Q:K 0.8~1.2

 

EP 08 Grade:

Flavone glycosides 22~27% / Terpene lactones 5.0~7.00% / Ginkgolic Acid<5PPM /
 

4. Function and Use

Mechanisms of action of Ginkgo biloba extract includes antioxidant, neurotransmitter/receptor modulatory, and antiplatelet activating factor properties. GBE is effective in treating some of the neurologic sequelae associated with Alzheimer's disease, traumatic brain injury (TBI), stroke, normal aging, edema, tinnitus, and macular degeneration.

GBE is today widely applied in medicine and dietary supplements.
 
5. Packaging

25kg/drum

 

6.Storage

Sealed store in a cool, dry place away from direct sunlight

 
 
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First edition created on July 13,1998 Last updated on September 20,2017